Generic top-level domain

Generic top-level domains (gTLDs) are one of the categories of top-level domains (TLDs) maintained by the Internet Assigned Numbers Authority (IANA) for use in the Domain Name System of the Internet. A top-level domain is the last label of every fully qualified domain name. They are called generic for historic reasons; initially, they were contrasted with country-specific TLDs in RFC 920.

The core group of generic top-level domains consists of the com, info, net, and org domains. In addition, the domains biz, name, and pro are also considered generic; however, these are designated as restricted, because registrations within them require proof of eligibility within the guidelines set for each.

Historically, the group of generic top-level domains included domains, created in the early development of the domain name system, that are now sponsored by designated agencies or organizations and are restricted to specific types of registrants. Thus, domains edu, gov, int, and mil are now considered sponsored top-level domains, much like the themed top-level domains (e.g., jobs). The entire group of domains that do not have a geographic or country designation (see country-code top-level domain) is still often referred to by the term generic TLDs.

Shut Out (album)

Shut Out is the debut album by American actor, singer and songwriter Paul Jabara.

The album which was released on the Casablanca Records label in 1977 includes the singles "Shut Out" (a duet with Donna Summer), "Dance" and "Slow Dancing". The original LP was pressed on red vinyl.

Shut Out has yet to be re-released on CD.

Track listing

Dance (Disco Heat)

"Dance (Disco Heat)" is the title of a 1978 single by American disco singer Sylvester James, who performed using just his first name, Sylvester. The song became Sylvester's first Top 40 hit in the US, where it peaked at #19 on the Billboard Hot 100 chart in the fall of 1978; it also reached #29 on the UK Singles Chart. The song appears on his 1978 album, Step II.

A 12" single was released in 1978, with "Dance (Disco Heat)" as the A-side and "You Make Me Feel (Mighty Real)" as the B-side, and these two extended dance mixes proved to be very popular in the dance clubs at the time. The two songs held down the top spot on the Billboard Dance/Disco chart for six weeks in August and September of that year and helped to establish Sylvester's career as a noted disco and dance music performer, both in the U.S. and abroad.

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Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase

Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase (EC 3.1.3.86, SHIP1, SHIP2, SHIP, p150Ship) is an enzyme with system name 1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 5-phosphohydrolase. This enzyme catalyses the following chemical reaction

This enzyme hydroylses 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2.

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